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1

Characteristics of gas hydrate reservoirs and their effect on petrophysical properties in the Muli area, Qinghai-Tibetan plateau permafrost

Peng, Cheng, Zou, Changchun, Lu, Zhenquan, Yu, Changqing, Liu, Anqi, Tang, Yeye, Hu, Xudong, Zhang, Shuxia, Wen, Huaijun, Li, Yonghong, Wang, Weichao

Journal:

Journal of Natural Gas Science and Engineering

Année:

2018

Langue:

english

Fichier:

PDF, 8.06 MB

english, 2018

2

Effects of Spacers on Surface Activities and Aggregation Properties of Anionic Gemini Surfactants

Xulong Cao, Zhenquan Li, Xinwang Song, Xiaohong Cui, Yuping Wei, Fa Cheng, Jun Wang

Journal:

Journal of Surfactants and Detergents

Année:

2009

Langue:

english

Fichier:

PDF, 300 KB

english, 2009

3

Indefinite article or numeral one?: A Study of iʔ5 ‘one’ in Shiposheng

Zhang, Qingwen, Cheng, Zhenquan, Tang, Sze-Wing, Liu, Hongyong

Journal:

International Journal of Chinese Linguistics

Année:

2015

Langue:

english

Fichier:

PDF, 291 KB

english, 2015

4

Hydrocarbon source for oil and gas indication associated with gas hydrate and its significance in the Qilian Mountain permafrost, Qinghai, Northwest China

Cheng, Bin, Xu, Jianbing, Lu, Zhenquan, Li, Yonghong, Wang, Weichao, Yang, Shan, Liu, Hu, Wang, Ting, Liao, Zewen

Journal:

Marine and Petroleum Geology

Année:

2017

Langue:

english

Fichier:

PDF, 3.59 MB

english, 2017

5

Discovery of N -(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) as a potent ALK/EGFR dual kinase inhibitor capable of overcoming a variety of ALK/EGFR associated drug resistant mutants in NSCLC

Chen, Yongfei, Wu, Jiaxin, Wang, Aoli, Qi, Ziping, Jiang, Taoshan, Chen, Cheng, Zou, Fengming, Hu, Chen, Wang, Wei, Wu, Hong, Hu, Zhenquan, Wang, Wenchao, Wang, Beilei, Wang, Li, Ren, Tao, Zhang, Shan

Journal:

European Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 12.36 MB

english, 2017

6

Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia

Liu, Xuesong, Wang, Beilei, Chen, Cheng, Jiang, Zongru, Hu, Chen, Wu, Hong, Zhang, Yicong, Liu, Xiaochuan, Wang, Wenliang, Wang, Junjie, Hu, Zhenquan, Wang, Aoli, Huang, Tao, Liu, Qingwang, Wang, Wei,

Journal:

European Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 3.13 MB

english, 2018

7

Axitinib overcomes multiple imatinib resistant cKIT mutations including the gatekeeper mutation T670I in gastrointestinal stromal tumors

Liu, Feiyang, Zou, Fengming, Chen, Cheng, Yu, Kailin, Liu, Xiaochuan, Qi, Shuang, Wu, Jiaxin, Hu, Chen, Hu, Zhenquan, Liu, Juan, Liu, Xuesong, Wang, Li, Ge, Juan, Wang, Wenchao, Ren, Tao, Bai, Mingfen

Journal:

Therapeutic Advances in Medical Oncology

Année:

2019

Langue:

english

Fichier:

PDF, 1.88 MB

english, 2019

8

Core-shell type multiarm star poly(ε-caprolactone) with high molecular weight hyperbranched polyethylenimine as core: Synthesis, characterization and encapsulation properties

Xulong Cao, Zhenquan Li, Xinwang Song, Xiaohong Cui, Pengfei Cao, Huaji Liu, Fa Cheng, Yu Chen

Journal:

European Polymer Journal

Année:

2008

Langue:

english

Fichier:

PDF, 673 KB

english, 2008

9

Monoclonal antibody, a novel probe for protein folding

Peng Cheng, Xide Wang, Guozhong Jing, Kangyuan Zhao, Junmei Zhou, Zhenquan Guo

Journal:

SCIENCE CHINA Life Sciences

Année:

1998

Langue:

english

Fichier:

PDF, 405 KB

english, 1998

10

Robust face detection and analysis

Zhenquan Zhuang, Yimin Cheng, Qibin Sun, Yixiao Wang

Journal:

Journal of Electronics (China)

Année:

2000

Langue:

english

Fichier:

PDF, 994 KB

english, 2000

11

Preparation and electrical properties of (1 − x)Sr(Fe1/2Nb1/2)O3–xPbTiO3 ferroelectric ceramics

Bijun Fang, Zhenquan Cheng, Renbing Sun, Chenlu Ding

Journal:

Journal of Alloys and Compounds

Année:

2009

Langue:

english

Fichier:

PDF, 935 KB

english, 2009

12

Supramolecular vesicles of cationic gemini surfactants modulated byp-sulfonatocalix[4]arene

ZhenQuan Li, ChunXiu Hu, YuQiao Cheng, Hui Xu, XuLong Cao, XinWang Song, HengYi Zhang, Yu Liu

Journal:

Science China Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 747 KB

english, 2012

13

[IEEE 2013 Ninth International Conference on Mobile Ad-hoc and Sensor Networks (MSN) - Dalian, China (2013.12.11-2013.12.13)] 2013 IEEE 9th International Conference on Mobile Ad-hoc and Sensor Networks - Gatewaying the Wireless Sensor Networks

Yue, Wenlong, Zhang, Yuanyuan, Qin, Zhenquan, Zhu, Ming, Jin, Cheng, Wang, Lei, Shu, Lei, Chen, Canfeng

Année:

2013

Langue:

english

Fichier:

PDF, 226 KB

english, 2013

14

[IEEE ICC 2012 - 2012 IEEE International Conference on Communications - Ottawa, ON, Canada (2012.06.10-2012.06.15)] 2012 IEEE International Conference on Communications (ICC) - A green solution for intelligent metropolitan heating system with uSDCards

Yue, Wenlong, Wang, Lei, Jin, Cheng, Liu, Xiaokang, Zhu, Ming, Qin, Zhenquan, Chen, Canfeng

Année:

2012

Langue:

english

Fichier:

PDF, 231 KB

english, 2012

15

Discovery of 2-((3-amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a potent, selective and orally available BCR-ABL/SRC/p38 kinase inhibitor for Chronic Myeloid Leukemia

Liang, Xiaofei, Liu, Xiaochuan, Wang, Beilei, Zou, Fengming, Wang, Aoli, Qi, Shuang, Chen, Cheng, Zhao, Zheng, Wang, Wenchao, Qi, Ziping, Lv, Fengchao, Hu, Zhenquan, Wang, Li, Zhang, Shanchun, Liu, Qi

Journal:

Journal of Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 2.97 MB

english, 2016

16

Discovery of N -(3-((1-Isonicotinoylpiperidin-4-yl)oxy)-4-methylphenyl)-3-(trifluoromethyl)benzamide (CHMFL-KIT-110) as a Selective, Potent, and Orally Available Type II c-KIT Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs)

Wang, Qiang, Liu, Feiyang, Wang, Beilei, Zou, Fengming, Chen, Cheng, Liu, Xiaochuan, Wang, Aoli, Qi, Shuang, Wang, Wenchao, Qi, Ziping, Zhao, Zheng, Hu, Zhenquan, Wang, Wei, Wang, Li, Zhang, Shanchun,

Journal:

Journal of Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 9.98 MB

english, 2016

17

Ensemble Learning for Independent Component Analysis of Normal Galaxy Spectra

Lu, Honglin, Zhou, Hongyan, Wang, Junxian, Wang, Tinggui, Dong, Xiaobo, Zhuang, Zhenquan, Li, Cheng

Journal:

The Astronomical Journal

Année:

2006

Langue:

english

Fichier:

PDF, 2.77 MB

english, 2006

18

Discovery of N-((1-(4-(3-(3-((6,7-dimethoxyquinolin-3-yl)oxy)phenyl)ureido)-2-(trifluoromethyl)phenyl)piperidin-4-yl)methyl)propionamide (CHMFL-KIT-8140) as a Highly Potent Type II Inhibitor Capable of Inhibiting the T670I “Gatekeeper” Mutant of cKIT Kinase

Li, Binhua, Wang, Aoli, Liu, Juan, Qi, Ziping, Liu, Xiaochuan, Yu, Kailin, Wu, Hong, Chen, Cheng, Hu, Chen, Wang, Wenchao, Wu, Jiaxin, Hu, Zhenquan, Ye, Ling, Zou, Fengming, Liu, Feiyang, Wang, Beilei

Journal:

Journal of Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 14.56 MB

english, 2016

19

Discovery of 4-Methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl) phenyl)-3-((1-nicotinoylpiperidin-4-yl)oxy)benzamide (CHMFL-ABL/KIT-155) as a Novel Highly Potent Type II ABL/KIT Dual Kinase Inhibitor with a Distinct Hinge Binding

Wang, Qiang, Liu, Feiyang, Wang, Beilei, Zou, Fengming, Qi, Ziping, Chen, Cheng, Yu, Kailin, Hu, Chen, Qi, Shuang, Wang, Wenchao, Hu, Zhenquan, Liu, Juan, Wang, Wei, Wang, Li, Liang, Qianmao, Zhang, S

Journal:

Journal of Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 3.43 MB

english, 2016

20

Discovery of 2-((3-Acrylamido-4-methylphenyl)amino)- N -(2-methyl-5-(3,4,5-trimethoxybenzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-BMX-078) as a Highly Potent and Selective Type II Irreversible Bone Marrow Kinase in the X Chromosome (BMX) Kinase Inhibitor

Liang, Xiaofei, Lv, Fengchao, Wang, Beilei, Yu, Kailin, Wu, Hong, Qi, Ziping, Jiang, Zongru, Chen, Cheng, Wang, Aoli, Miao, Weili, Wang, Wenchao, Hu, Zhenquan, Liu, Juan, Liu, Xiaochuan, Zhao, Zheng,

Journal:

Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 7.27 MB

english, 2017

21

Discovery of N -(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl)phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-( tert -butyl)benzamide (CHMFL-BTK-01) as a highly selective irreversible Bruton's tyrosine kinase (BTK) inhibitor

Liang, Qianmao, Chen, Yongfei, Yu, Kailin, Chen, Cheng, Zhang, Shouxiang, Wang, Aoli, Wang, Wei, Wu, Hong, Liu, Xiaochuan, Wang, Beilei, Wang, Li, Hu, Zhenquan, Wang, Wenchao, Ren, Tao, Zhang, Shanchu

Journal:

European Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 4.64 MB

english, 2017

22

Structure-activity relationship investigation for benzonaphthyridinone derivatives as novel potent Bruton's tyrosine kinase (BTK) irreversible inhibitors

Wang, Beilei, Deng, Yuanxin, Chen, Yongfei, Yu, Kailin, Wang, Aoli, Liang, Qianmao, Wang, Wei, Chen, Cheng, Wu, Hong, Hu, Chen, Miao, Weili, Hur, Wooyoung, Wang, Wenchao, Hu, Zhenquan, Weisberg, Ellen

Journal:

European Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 3.99 MB

english, 2017

23

Discovery of 1-(4-(4-Amino-3-(4-(2-morpholinoethoxy)phenyl)-1H-pyrazolo[3,4-d] pyrimidin-1-yl)phenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea (CHMFL-FLT3-213) as a Highly Potent Type II FLT3 Kinase Inhibitor Capable of Overcoming a Variety of FLT3 Kinase Mutants in FLT3-ITD Positive AML

Wang, Aoli, Li, Xixiang, Chen, Cheng, Wu, Hong, Qi, Ziping, Hu, Chen, Yu, Kailin, Wu, Jiaxin, Liu, Juan, Liu, Xiaochuan, Hu, Zhenquan, Wang, Wei, Wang, Wenliang, Wang, Wenchao, Wang, Li, Wang, Beilei,

Journal:

Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 2.88 MB

english, 2017

24

Discovery of 4-(( N -(2-(dimethylamino)ethyl)acrylamido)methyl)- N -(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia

Wang, Qiang, Liu, Feiyang, Qi, Shuang, Qi, Ziping, Yan, Xiao-E., Wang, Beilei, Wang, Aoli, Wang, Wei, Chen, Cheng, Liu, Xiaochuan, Jiang, Zongru, Hu, Zhenquan, Wang, Li, Wang, Wenchao, Ren, Tao, Zhang

Journal:

European Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 4.99 MB

english, 2018

25

Phytonutrient genistein is a survival factor for pancreatic β-cells via GPR30-mediated mechanism

Luo, Jing, Wang, Aihua, Zhen, Wei, Wang, Yao, Si, Hongwei, Jia, Zhenquan, Alkhalidy, Hana, Cheng, Zhiyong, Gilbert, Elizabeth, Xu, Bin, Liu, Dongmin

Journal:

The Journal of Nutritional Biochemistry

Année:

2018

Langue:

english

Fichier:

PDF, 6.07 MB

english, 2018

26

Small Molecule Kaempferol Promotes Insulin Sensitivity and Preserved Pancreatic β -Cell Mass in Middle-Aged Obese Diabetic Mice

Alkhalidy, Hana, Moore, William, Zhang, Yanling, McMillan, Ryan, Wang, Aihua, Ali, Mostafa, Suh, Kyung-Shin, Zhen, Wei, Cheng, Zhiyong, Jia, Zhenquan, Hulver, Matthew, Liu, Dongmin

Journal:

Journal of Diabetes Research

Année:

2015

Langue:

english

Fichier:

PDF, 2.95 MB

english, 2015

27

Discovery of ( S )-2-amino- N -(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3Kδ) inhibitor

Liang, Xiaofei, Li, Feng, Chen, Cheng, Jiang, Zongru, Wang, Aoli, Liu, Xiaochuan, Ge, Juan, Hu, Zhenquan, Yu, Kailin, Wang, Wenliang, Zou, Fengming, Liu, Qingwang, Wang, Beilei, Wang, Li, Zhang, Shanc

Journal:

European Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 3.03 MB

english, 2018

28

Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino)cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor

Wang, Beilei, Wu, Jiaxin, Wu, Yun, Chen, Cheng, Zou, Fengming, Wang, Aoli, Wu, Hong, Hu, Zhenquan, Jiang, Zongru, Liu, Qingwang, Wang, Wei, Zhang, Yicong, Liu, Feiyang, Zhao, Ming, Hu, Jie, Huang, Tao

Journal:

European Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 4.00 MB

english, 2018

29

Discovery of N-(4-(6-acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent Fms-like Tyrosine Kinase 3 Internal Tandem Duplications (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia

Liang, Xiaofei, Wang, Beilei, Chen, Cheng, Wang, Aoli, Hu, Chen, Zou, Fengming, Yu, Kailin, Liu, Qingwang, Li, Feng, Hu, Zhenquan, Lu, Tingting, Wang, Junjie, Wang, Li, Weisberg, Ellen, Li, Lili, Xia,

Journal:

Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 1.98 MB

english, 2018

30

Evaluation of gas hydrate saturation by effective medium theory in shaly sands: a case study from the Qilian Mountain permafrost, China

Hu, Xudong, Zou, Changchun, Lu, Zhenquan, Yu, Changqing, Peng, Cheng, Li, Wei, Tang, Yeye, Liu, Anqi, Kouamelan, Kouamelan Serge

Journal:

Journal of Geophysics and Engineering

Année:

2019

Fichier:

PDF, 4.82 MB

2019

31

Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML)

Wu, Jiaxin, Wang, Aoli, Li, Xixiang, Chen, Cheng, Qi, Ziping, Hu, Chen, Wang, Wenliang, Wu, Hong, Huang, Tao, Zhao, Ming, Wang, Wenchao, Hu, Zhenquan, Liu, Qingwang, Wang, Beilei, Wang, Li, Li, Lili,

Journal:

Cancer Biology & Therapy

Année:

2019

Langue:

english

Fichier:

PDF, 3.55 MB

english, 2019

32

Evaluation of gas hydrate saturation by effective medium theory in shaly sands: a case study from the Qilian Mountain permafrost, China

Hu, Xudong, Zou, Changchun, Lu, Zhenquan, Yu, Changqing, Peng, Cheng, Li, Wei, Tang, Yeye, Liu, Anqi, Kouamelan, Kouamelan Serge

Journal:

Journal of Geophysics and Engineering

Année:

2019

Langue:

english

Fichier:

PDF, 4.82 MB

english, 2019

33

Discovery of (E)-N1-(3-fluorophenyl)-N3-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)malonamide (CHMFL-KIT-033) as a Novel c-KIT T670I Mutant Selective Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs)

Liu, Xuesong, Wang, Beilei, Chen, Cheng, Qi, Ziping, Zou, Fengming, Wang, Junjie, Hu, Chen, Wang, Aoli, Ge, Juan, Liu, Qingwang, Yu, Kailin, Hu, Zhenquan, Jiang, Zongru, Wang, Wei, Wang, Li, Wang, Wen

Journal:

Journal of Medicinal Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 1.79 MB

english, 2019

34

Discovery of 6′-chloro-N-methyl-5’-(phenylsulfonamido)-[3,3′-bipyridine]-5-carboxamide (CHMFL-PI4K-127) as a novel Plasmodium falciparum PI(4)K inhibitor with potent antimalarial activity against both blood and liver stages of Plasmodium

Liang, Xiaofei, Jiang, Zongru, Huang, Zhenghui, Li, Feng, Chen, Cheng, Hu, Chen, Wang, Wenliang, Hu, Zhenquan, Liu, Qingwang, Wang, Beilei, Wang, Li, Qi, Ziping, Liu, Jing, Jiang, Lubin, Liu, Qingsong

Journal:

European Journal of Medicinal Chemistry

Année:

2020

Fichier:

PDF, 2.99 MB

2020

35

Cantharidin-loaded functional mesoporous titanium peroxide nanoparticles for non-small cell lung cancer targeted chemotherapy combined with high effective photodynamic therapy

Zheng, Kun, Chen, Runze, Sun, Yanxue, Tan, Zhenquan, Liu, Ye, Cheng, Xiao, Leng, Junke, Guo, Zhaoming, Xu, Pengcheng

Journal:

Thoracic Cancer

Année:

2020

Langue:

english

Fichier:

PDF, 5.40 MB

english, 2020

36

Discovery of (E)-N-(4-methyl-5-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thiazol-2-yl)-2-(4-methylpiperazin-1-yl)acetamide (IHMT-TRK-284) as a novel orally available type II TRK kinase inhibitor capable of overcoming multiple resistant mutants

Wang, Beilei, Zhang, Wentao, Liu, Xuesong, Zou, Fengming, Wang, Junjie, Liu, Qingwang, Wang, Aoli, Hu, Zhenquan, Chen, Yongfei, Qi, Shuang, Jiang, Zongru, Chen, Cheng, Hu, Chen, Wang, Li, Wang, Wencha

Journal:

European Journal of Medicinal Chemistry

Année:

2020

Fichier:

PDF, 7.88 MB

2020

37

[IEEE 2020 12th IEEE PES Asia-Pacific Power and Energy Engineering Conference (APPEEC) - Nanjing, China (2020.9.20-2020.9.23)] 2020Â 12th IEEEÂ PES Asia-Pacific Power and Energy Engineering Conference (APPEEC) - Optimal Configuration Strategy of Dynamic and Static Reactive Power Compensation Equipment for DC Converter Station

Liu, Bailiang, Wang, Weiyuan, Cheng, Jinmin, Le, Xiaorong, Wang, Zhenquan

Année:

2020

Fichier:

PDF, 224 KB

2020

38

Discovery of ( S )-2-(1-(4-Amino-3-(3-fluoro-4-methoxyphenyl)-1 H -pyrazolo[3,4- d ]pyrimidin-1-yl)propyl)-3-cyclopropyl-5-fluoroquinazolin-4(3 H )-one (IHMT-PI3KÎ´-372) as a Potent and Selective PI3KÎ´ Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease

Li, Feng, Liang, Xiaofei, Jiang, Zongru, Wang, Aoli, Wang, Junjie, Chen, Cheng, Wang, Wenliang, Zou, Fengming, Qi, Ziping, Liu, Qingwang, Hu, Zhenquan, Cao, Jiangyan, Wu, Hong, Wang, Beilei, Wang, Li,

Journal:

Journal of Medicinal Chemistry

Année:

2020

Fichier:

PDF, 6.73 MB

2020